Fantasy Football Week 12: Start'em or Sit'em This Thanksgiving Day Weekend

Week 12 kicks off this Thursday, and before you sit back with a plate of Grandma's finest, don't forget to set your fantasy lineups.

Sure, we will be feasting our eyes on three tasty games this holiday, but once your lineup is locked in, there's no going back, so this list isn't limited to only Thursday's games.

Here are 10 starts and sits that could be the difference in whether or not you're thankful for your fantasy squad this weekend.

Start Em: Marques Colston

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NEW ORLEANS - NOVEMBER 21: Marques Colston #12 of the New Orleans Saints pulls in this reception against the Seattle Seahawks at Louisiana Superdome on November 21, 2010 in New Orleans, Louisiana. (Photo by Kevin C. Cox/Getty Images)

Colston is New Orleans' leading receiver, and this Thanksgiving, he and the Saints visit the Dallas Cowboys, winners of two straight games.

Fortunately for the road team, the Cowboys have one of the league's most porous secondaries.

Look for quarterback Drew Brees to target the large frame of Marques Colston a few times on Thursday; he isn't a bad start.

Sit Em: Cedric Benson

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CINCINNATI - NOVEMBER 21: Cedric Benson #32 of the Cincinnati Bengals runs with the ball during the NFL game against the Buffalo Bills at Paul Brown Stadium on November 21, 2010 in Cincinnati, Ohio. (Photo by Andy Lyons/Getty Images)

Cedric Benson has been a rare bright spot for the 2-8 Bengals this season, but Thursday night, he will be going up against one of the NFL's best defenses in the New York Jets.

Benson has been a reliable fantasy prospect all year long with 200 carries, over 740 yards rushing and five total touchdowns.

However, Cincinnati has reached a new low after losing at home to the Bills by 18 points on Sunday, after being outscored 35-0 in the second half.

Look for some uninspired Bengals on the field Thursday night and very little fantasy production from Benson.

Start Em: Mike Tolbert

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SAN DIEGO - OCTOBER 31: Running back Mike Tolbert #35 of the San Diego Chargers celebrates a touchdown against the Tennessee Titans during the game at Qualcomm Stadium on October 31, 2010 in San Diego, California. The Chargers defeated the Titans 33-25.

Tolbert is as hot as they come after last Monday night's performance against the Broncos.

Though it was just Tolbert's second 100-yard rushing game of the season, his 506 rushing yards and eight touchdowns on only 112 attempts is rather eye-opening.

The Chargers are in Indianapolis this Sunday night, and the Colts banged up defense might equal a huge fantasy day for Tolbert and his Charger running mates.

Sit Em: Michael Turner

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ATLANTA - NOVEMBER 11: Michael Turner #33 of the Atlanta Falcons waits to enter the field during player introductions before facing the Baltimore Ravens at Georgia Dome on November 11, 2010 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

The Falcons host the Packers on Sunday in the Georgia Dome, but the Green Bay run defense might have the home field advantage in this one.

The Packers defense has been phenomenal as of late, shutting down Adrian Peterson last Sunday, Marion Barber three weeks ago, and before that, the Jets' running game was victimized.

Sure, Turner is one of the league's premier running backs and is an excellent fantasy player, but his match up this week isn't favorable, bench him only if you have another back with a better matchup.

Start Em: Donovan McNabb

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NASHVILLE, TN - NOVEMBER 21: Quarterback Donovan McNabb #5 of the Washington Redskins drops back to pass against the Tennessee Titans at LP Field on November 21, 2010 in Nashville, Tennessee. The Redskins won 19-16 in overtime. (Photo by Grant Halverson

McNabb and the Redskins are slightly back on track after a road win over the Titans last week, and this Sunday they play host to the dysfunction that is the Minnesota Vikings.

The Minnesota secondary was torched by the Packers last week, and McNabb is fresh off of a 30 completion and 376-yard performance.

Look for McNabb to put up some healthy fantasy numbers at quarterback this week, considering most opposing quarterbacks have done well against the Vikings this season; they are 0-5 on the road.

Sit Em: Jason Witten

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ARLINGTON, TX - OCTOBER 31: Jaosn Witten #82 of the Dallas Cowboys looks on against the Jacksonville Jaguars at Cowboys Stadium on October 31, 2010 in Arlington, Texas. (Photo by Ronald Martinez/Getty Images)

Jason Witten's production has diminished with the Cowboys' playoff hopes.

Dallas is home to New Orleans this Sunday, and this week doesn't appear to be the one that backup quarterback Jon Kitna begins to target Witten more.

Witten has just eight receptions in the past three games, and that certainly doesn't bode well for fantasy owners.  Sit Witten.

Start Em: BenJarvus Green-Ellis

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FOXBORO, MA - NOVEMBER 21: BenJarvus Green-Ellis #42 of the New England Patriots gains yards against the Indianapolis Colts in the second half at Gillette Stadium on November 21, 2010 in Foxboro, Massachusetts. (Photo by Jim Rogash/Getty Images)

BenJarvus Green-Ellis' name isn't the only thing getting him attention, his play on the field as of late has caused many NFL fans to take notice.

Green-Ellis and the Patriots will kick off Week 12 on the road in Detroit on Thanksgiving Day. Look for the back to pick up where he left off last week against Indianapolis with another big game.

It seems as if Green-Ellis is a lock for 20 carries, 100 yards and a touchdown week in and week out.

Sit Em: Jay Cutler

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MIAMI - NOVEMBER 18: Quarterback Jay Cutler #6 of the Chicago Bears scrambles against the Miami Dolphins at Sun Life Stadium on November 18, 2010 in Miami, Florida. (Photo by Marc Serota/Getty Images)

Jay Cutler and the Bears host the soaring Eagles on Sunday. Not exactly a favorable matchup for the interception-prone quarterback.

Asante Samuel has terrorized opposing quarterbacks this season, and the Philadelphia defense is coming off a near-dominating performance against the Giants last Sunday night.

Cutler has been known to lock onto receivers when he is pressured, and remember, interceptions can cost you points in fantasy football. Sit Cutler this week.

Start Em: Nate Washington

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INDIANAPOLIS - DECEMBER 06: Nate Washington #85 of the Tennessee Titans looks on during the NFL game against the Indianapolis Colts at Lucas Oil Stadium on December 6, 2009 in Indianapolis, Indiana. (Photo by Andy Lyons/Getty Images)

The Titans' receiver is going up against the worst pass defense in the NFL in the Houston Texans.

Houston's secondary has been almost invisible the past two weeks after giving up game-winning touchdowns through the air to lose each game.

Regardless of who starts at quarterback for Tennessee, look to start Nate Washington, he is the team's leading receiver and is sure to get open against Houston.

Sit Em: Josh Freeman

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ATLANTA - NOVEMBER 07: Quarterback Josh Freeman #5 of the Tampa Bay Buccaneers against the Atlanta Falcons at Georgia Dome on November 7, 2010 in Atlanta, Georgia. (Photo by Kevin C. Cox/Getty Images)

The second-year quarterback has been as solid as it gets for the Buccaneers this season, throwing for 14 touchdowns to only five interceptions.

But Sunday, Freeman will face a totally different kind of beast when he lines up against the Baltimore Ravens defense and playmaker extraordinaire Ed Reed.

The Ravens are undefeated at home and this matchup looks daunting for Freeman and the Buccaneers. Try sitting him this week.

Patrick Clarke is a student at Towson University and a writing intern for Bleacher Report. Follow on Twitter @PjamesC