K.C. added Edwards-Helaire to their already star-studded offense in the first round of the 2020 NFL draft. He enjoyed a strong rookie campaign to the tune of 1,100 yards from scrimmage and five total touchdowns across 13 appearances last year.
The 22-year-old LSU product missed the end of the regular season and the start of the Chiefs' playoff run with a high-ankle sprain in 2020. He suffered another ankle injury during this year's preseason.
Entering Week 5, he tallied 291 rushing yards.
Darrel Williams figures to lead a Chiefs backfield committee whenever Edwards-Helaire is unavailable. Jerick McKinnon and Michael Burton are among the other options to handle carries.
Kansas City's offense leans heavily on the Patrick Mahomes-led passing game, making it easier to make up for an absence in the rushing attack. However, Edwards-Helaire brings a dual-threat element the unit will miss if he's sidelined.