According to Major League Baseball's press release, the Indians-Twins series will take place at Hiram Bithorn Stadium in San Juan, Puerto Rico, on April 17 and 18, with the Twins serving as the home team for both games.
Indians All-Star shortstop Francisco Lindor, who is from Puerto Rico and represented the country during the 2017 World Baseball Classic, expressed his excitement to play in front of his countrymen in MLB's press release:
"It is a dream come true for me to play in Puerto Rico. When the Montreal Expos played in Puerto Rico, I remember going to those games and thinking to myself, 'I would love to be here playing in front of my country and people.' Now that we have the opportunity next April, it is a dream realized for me. These will be the most memorable regular season games of my career, for sure."
In August 2016, MLB and the MLB Players Association announced a $5 million commitment to building and supporting baseball programs in Puerto Rico.
The 2003-04 Montreal Expos used Puerto Rico as their home for 43 regular-season games. The last regular-season contests to be played in the country were in 2010 between the Florida Marlins and New York Mets.