Twitter Reacts to Michigan State's Upset Loss to Middle Tennessee

And the madness marches on.

The No. 15 Middle Tennessee Blue Raiders upset the second-seeded Michigan State Spartans, 90-81, in the round of 64 on Friday. Just six brackets remained un-busted in the perfect bracket challenge, per ESPN Fantasy Sports.

And right on cue, the Twitter reactions poured in. Here are some of our favorite march sadness takes (crying Jordans included):

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pic.twitter.com/vbVin1CCjg

— Crying Jordan (@crying_jordan) March 18, 2016"

[Twitter]