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\Latest NFL Odds and Picks Factoring in New Weather Forecasts for Week 7 Schedule

Kristopher KnoxOct 21, 2026

We have one more full slate of October games on the schedule. While that's usually too early for NFL teams to be dealing with must-win scenarios, we are looking at a few of those in Week 7.

The Los Angeles Rams, for example, fell to 2-4 on Sunday and can't afford another loss if they hope to remain relevant in the NFC West race. The Indianapolis Colts, meanwhile, just fired GM Chris Ballard and could make more significant changes if Indy slips to 2-5 this week.

The mounting pressure will be a factor for several teams. Weather is likely to impact a few more.

Here, we'll take an early look at the Week 7 slate, the latest odds, and the most accurate forecast information from The Weather Channel to make a few predictions.

NFL Week 7 Schedule

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Bears Falcons Football
Bears QB Caleb Williams

Thursday, October 22

New England Patriots (+3) at Chicago Bears

Schedule: 8:15 p.m. ET on Prime Video

Forecast: Mostly Clear Skies, Low of 51°F

Prediction: Patriots

Sunday, October 25

Pittsburgh Steelers (-3) vs. New Orleans Saints (in Paris)

Schedule: 9:30 a.m. ET on NFL Network

Forecast: Chance of Rain, Winds up to 20MPH, High of 60°F

Prediction: Saints

San Francisco 49ers (-3.5) at Atlanta Falcons (Retractable Roof)

Schedule: 1 p.m. ET on Fox

Forecast: Sunny, High of 71°F

Prediction: 49ers

Cincinnati Bengals (+2.5) at Baltimore Ravens

Schedule: 1 p.m. ET on CBS

Forecast: Sunny, High of 68°F

Prediction: Bengals

Tampa Bay Buccaneers (+3.5) at Carolina Panthers

Schedule: 1 p.m. ET on Fox

Forecast: Sunny, High of 70°F

Prediction: Buccaneers

New York Giants (+9.5) at Houston Texans (Retractable Roof)

Schedule: 1 p.m. ET on Fox

Forecast: Mostly Cloudy, High of 84°F

Prediction: Giants

Indianapolis Colts (+6.5) at Minnesota Vikings (Dome)

Schedule: 1 p.m. ET on CBS

Forecast: N/A

Prediction: Vikings

Miami Dolphins (+4.5) at New York Jets

Schedule: 1 p.m. ET on CBS

Forecast: Sunny, High of 68°F

Prediction: Dolphins

Cleveland Browns (-1.5) at Tennessee Titans

Schedule: 1 p.m. ET on CBS

Forecast: Partly Cloudy, High of 78°F

Prediction: Browns

Denver Broncos (-4.5) at Arizona Cardinals (Retractable Roof)

Schedule: 4:05 p.m. ET on CBS

Forecast: Mostly Sunny, High of 82°F

Prediction: Broncos

Green Bay Packers (+3) at Detroit Lions (Dome)

Schedule: 4:25 p.m. ET on Fox

Forecast: N/A

Prediction: Packers

Los Angeles Rams (-4.5) at Las Vegas Raiders (Dome)

Schedule: 4:25 p.m. ET on Fox

Forecast: N/A

Prediction: Rams

Kansas City Chiefs (+2.5) at Seattle Seahawks

Schedule: 8:20 p.m. ET on NBC

Forecast: Mostly Cloudy, Low of 45°F

Prediction: Chiefs

Monday, October 26

Dallas Cowboys (-4.5) at Philadelphia Eagles

Schedule: 8:15 p.m. ET on ESPN

Forecast: Partly Cloudy, Low of 50°F

Prediction: Eagles

Byes: Buffalo Bills, Jacksonville Jaguars, Los Angeles Chargers, Washington Commanders

*Odds from FanDuel Sportsbook

Week 7 Preview

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Chiefs QB Patrick Mahomes

If the early season is an accurate indication of what's to come, fans should probably expect the unexpected in Week 7.

Things will kick off with a Thursday night showdown between the Chicago Bears and New England Patriots. Caleb Williams returned to action for the Bears in Week 6, and Chicago's offense immediately returned to form. However, it's fair to wonder if the Bears' lackluster defense can corral the Patriots now that Drake Maye seems to have found his rhythm.

Sunday's action will begin at Sade de France in Paris, where the New Orleans Saints and Pittsburgh Steelers will face off. Pittsburgh is by far the better team on paper, but it needed to stage an epic comeback against the Tampa Bay Buccaneers on Sunday. Playing overseas and against another mobile quarterback in Tyler Shough could give the Steelers trouble.

Right now, the Paris game looks like the only one that could be heavily impacted by weather. Of course, things can change rapidly in late October. Temperatures could be a factor in places like Arizona, Tennessee, and Houston, however.

Weather will be a total non-factor when the Green Bay Packers take on the rival Detroit Lions late Sunday afternoon. Detroit has a high-powered offense and will be coming out of its bye week. However, the Lions' defense has struggled, especially against the pass, and Green Bay's passing game has started to find its groove. This one is going to be fun.

Sunday's nightcap between the Kansas City Chiefs and Seattle Seahawks will also be intriguing. Seattle's defense and home-field advantage will be tough to overcome, but it's fair to wonder if Sam Darnold can break out of his funk against an aggressive Chiefs defense.

It would help if the Seahawks had a quality rushing attack, which they don't. Kansas City does, and it'll bring Kenneth Walker III back to Seattle for a "revenge" game.

Monday's battle between the Dallas Cowboys and Philadelphia Eagles lost some luster when the Eagles announced that quarterback Jalen Hurts would miss the rest of the season while getting treatment for blood clots. However, Saquon Barkley could return this week, which would give Philly a real shot against a struggling Cowboys defense.