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Puka Nacua, Malik Nabers, NFL Injury Statuses and Fantasy Impact for Week 3

Joe Tansey
Sep 25, 2026

Puka Nacua will likely miss his second straight game of the early 2026 NFL season.

The Los Angeles Rams wide receiver is listed as doubtful for his team's Week 3 clash with the Denver Broncos.

The news is much better for Malik Nabers, who is on track to play for the New York Giants on Sunday.

Nabers' health might be the least of the concerns for fantasy football players with him on the roster since Jameis Winston didn't look great in backup duty for the injured Jaxson Dart on Monday.

Below is a look at all of the significant injury news affecting fantasy football matchups in Week 3.

1 p.m. ET Games

D.J. MooreQuestionable
Keon Colemanย Questionable
Jalen CokerQuestionable
Adonai Mitchellย Questionable
Nico CollinsOut
Alec PierceDid Not Practice Friday
Caleb DouglasOut
Tony PollardQuestionable
Tyjae SpearsQuestionable
Malik NabersFull Participant In Friday Practice
Rico DowdleOut
Michael Pittman Jr.Questionable
Jaylen WarrenQuestionable
Jadarian PriceFull Participant in Friday Practice
Jayden DanielsOut
Jakobi MeyersFull Participant in Friday Practice

4 p.m. ET Games

Sunday Night

Puka NacuaDoubtful
Marvin Mims Jr.ย Questionable
Jonah Colemanย Out
JK DobbinsFull Participant in Friday Practice

Monday Night

DeVonta SmithDNP Thursday
Dallas GoedertDNP Thursday
Saquon BarkleyLimited Participant in Thursday Practice
Caleb WilliamsDoubtful
Tyson BagentDNP Friday
Kyle MonangaiLimited Participant in Friday Practice

Puka Nacua Listed As Doubtful

Puka Nacua has a doubtful designation for Week 3.

Nacua did not practice on Friday due to the hip and groin injuries that forced him out of Week 2, per ESPN's Sarah Barshop.

ESPN's Adam Schefter noted, though, that Nacua could return as early as Week 4.

The Rams offense thrived in Nacua's absence in Week 2. Davante Adams had eight catches, 195 yards and two touchdowns. Terrance Ferguson recorded 54 yards and a score off six catches.

Ferguson is the better waiver-wire pickup of the two since Adams was widely drafted across most fantasy leagues.

No other Rams player had more than two catches in Week 2. It's not worth taking the risk with wide receivers further down the depth chart in a tough matchup with Denver.

Adonai Mitchell of the New York Jets and Houston's Jaylin Noel are two under-the-radar selections for Week 3.

The Jets and Texans face the Detroit Lions and Indianapolis Colts, respectively, who both have top-five pass-yard concessions in the NFL.

Mitchell has had as many targets as Garrett Wilson through two weeks, while Noel is second on the Texans in receiving yards.

Buffalo's Khalil Shakir and Keon Coleman are replacement options for Nacua as well. The high-flying Bills offense faces an struggling Los Angeles Chargers team at home on Sunday.

Malik Nabers Set To Play

Malik Nabers was a full participant in New York Giants practice on Thursday.

That was a big step in the right direction for the star wide receiver, who hurt his shoulder on Monday night in Los Angeles.

Nabers shouldn't have any injury concerns going into Week 3's home clash with the Tennessee Titans.

On paper, Nabers has an excellent matchup against one of the league's worst teams, but he needs Jameis Winston to be better in order to take full advantage of the Titans' defense.

Winston went 11-for-27 with 111 yards in relief duty on Monday night after Jaxson Dart went down with what turned out to be a season-ending knee injury.

New York's matchup is significantly easier against the Titans than it was versus the Rams. That's one of the primary reasons to trust the Giants to put up big numbers on Sunday.

DeVonta Smith eclipsed the 100-yard mark last week against the Titans and Garrett Wilson had 79 yards on six catches in Week 1.

The early precedent set by the Titans defense is that No. 1 wide receivers can feast against them. The hope for Nabers is that trend continues into Week 3, even with a backup quarterback tossing him the ball.