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Fantasy Football Week 12 Waiver-Wire Pickups, Rankings, Box Score Stat Projections

Erik BeastonNov 17, 2025

The Week 12 slate of games in the NFL feature some potential high-scoring affairs, which means there will be plenty of big fantasy days for some of the league's top stars.

From Puka Nacua with the Los Angeles Rams to Jahmyr Gibbs and Amon-Ra St. Brown of the Detroit Lions, to Christian McCaffrey of San Francisco and Jaxon Smith-Njigba of Seattle, all should see prolific days.

Where do those stars land in the weekly rankings, and who are two worthwhile waiver wire pickups to consider as potential breakout performers?

Find out in this preview.

Week 12 FLEX Rankings

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Falcons Colts Football

The rankings for Week 12 FLEX options are:

1. Jonathan Taylor, RB, Indianapolis Colts at Kansas City Chiefs

2. Puka Nacua, WR, Los Angeles Rams vs. Tampa Bay Buccaneers

3. Jaxon Smith-Njigba, WR, Seattle Seahawks at Tennessee Titans

4. Ja'Marr Chase, WR, Cincinnati Bengals vs. New England Patriots

5. Jahmyr Gibbs, RB, Detroit Lions vs. New York Giants

6. Bijan Robinson, RB, Atlanta Falcons at New Orleans Saints

7. Christian McCaffrey, RB, San Francisco 49ers vs. Carolina Panthers

8. James Cook, RB, Buffalo Bills at Houston Texans

9. Trey McBride, TE, Arizona Cardinals vs. Jacksonville Jaguars

10. Davante Adams, WR, Los Angeles Rams vs. Tampa Bay Buccaneers

11. Brock Bowers, TE, Las Vegas Raiders vs. Cleveland Browns

12. Amon-Ra St. Brown, WR, Detroit Lions vs. New York Giants

13. Rico Dowdle, RB, Carolina Panthers at San Francisco 49ers

14. Saquon Barkley, RB, Philadelphia Eagles at Dallas Cowboys

15. Tyler Warren, TE, Indianapolis Colts at Kansas City Chiefs

Waiver Wire: Michael Wilson, WR, Arizona Cardinals

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Packers Cardinals Football

Cardinals fans and fantasy managers alike found out Sunday which wide receiver will be quarterback Jacoby Brissett's top target when Michael Wilson emerged from the pack, catching 15 balls for 185 yards.

Before that, the most the third-year player had caught in a single game this season was four.

With Marvin Harrison Jr. out for an undetermined amount of time after suffering appendicitis, Brissett and the Arizona offense will be looking for a receiver to step up. Much as he did in Week 11, look for Wilson to be that player.

He faces a Jacksonville Jaguars defense giving up the tenth-most fantasy points to opposing wide receivers this season, making him an intriguing start for managers in deeper leagues or those in need of wideout help in Week 12.

Stat Projections: 8 receptions, 75 yards, TD

Chris Rodriguez Jr., RB, Washington Commanders

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Lions Commanders Football

It is running back by committee in Washington and Chris Rodriguez Jr. appears to have leap-frogged Jacory Croskey-Merritt as the lead back for the Commanders.

Rodriguez carried 15 times for 79 yards in Washington's Week 11 loss to the Miami Dolphins.

The third-year player has an unfavorable match-up in Week 12 against the Denver Broncos, who are allowing the fourth-fewest fantasy points to opposing running backs. Still, the Commanders are in the midst of a terrible season given the lofty expectations set entering the year and will have to find ways to get the ball in their playmakers' hands.

Rodriguez may not be the most explosive back on the field, but he has been more consistent of late than the alternative, so do not be surprised if the Commanders find ways to get the ball into his hands.

The emerging running back is a worthy add or stash for managers in deeper leagues or in need of help at the position.

Projected Stats: 15 carries, 65 yards, 2 receptions, 15 yards

All fantasy stats via FantasyPros.com.

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