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Manny Pacquiao v Mario Barrios - News Conference
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Manny Pacquiao vs. Mario Barrios Betting Odds, Picks, Props for Boxing Fight

Joe TanseyJul 18, 2025

Manny Pacquiao returns to the boxing ring for the first time in four years on Saturday to face Mario Barrios.

The 46-year-old Pacquiao is understandably an underdog given his lack of recent time in the ring.

WBC welterweight champion Barrios is 16 years younger than his opponent and has fought five more times than him over the last four years.

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Over 10.5 Rounds (-150)

Barrios hasn't been in the knockout business lately.

The 30-year-old won four of his last five fights by decision. He has a single win by knockout since 2022.

All three of Pacquiao's fights since he turned 40 went 12 rounds, including his last bout against Yordenis Ugรกsย in 2021.

Mario Barrios To Win By Decision (+200)

Barrios comes into Saturday with a 29-2-1 record, with 11 of those victories by decision.

While the statistics in his method of victory favor knockouts, Barrios has had more wins by decision recently.

If you're going to take the Over 10.5 rounds, it's a wise bet to take Barrios to win by decision at +200.

Pacquiao can still put up a fight, but it's hard to imagine he'll outbox a current titleholder for the duration of a bout.

Manny Pacquiao To Be Knocked Down (-125)

The 16-year age gap will show at some point in the contest.

At 46 and with one fight in the last four years, Pacquiao's in-ring movements could be slower than usual, which may lead to some vulnerable spots to be hit by Barrios at points of the match.

Barrios is the fresher boxer of the two, and it's not a huge surprise to see him at +225 to be knocked down.

Of course, Pacquiao's goal is to be competitive enough to win, but it may take him a few rounds to find his footing. Look for the knockdown to happen early on with Barrios in control of the contest.

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