Louisville quarterback Reggie Bonnafon was taken out of Saturday's game against Kentucky in the second quarter with a leg injury.
According to Jeff Greer of The Courier Journal, Bonnafon was taken back to the locker room with the help of trainers:
ESPN's Brett McMurphy reported that the signal caller would not return:
Louisville was already down one quarterback, as Will Gardner is out for the season after injuring his knee in a win against Boston College on November 8. Bonnafon took the reins last week against Notre Dame, helping to lead the Cardinals to a 31-28 win against Notre Dame despite completing just 8-of-21 passes.