Week 10 NFL Picks: Tips, Odds and Over/Under Predictions for Sunday

NFL Week 10 picks need to be turned in now while the odds and over/under marks are ripe.

Now that the lines have simmered in the pot for a number of days and both bettors and Las Vegas have influenced matters, savvy bettors will swoop in armed with the latest information and make some noteworthy headway in the financial department.

For those who enjoy using over/under odds as a way to pad other betting investments in an insurance-like manner, Week 10 is a safe haven that this season has truly yet to provide.

Below is a look at every line the rest of the week has to offer, with a few in-depth tips after the jump.

NFL Week 10 Picks Against the Spread

Matchup	Spread (Over/Under)	Pick ATS	O/U Pick	Reason
Kansas City at Buffalo	KC -2 (41.5)	KC	U	Kansas City's offense finally seems to be turning things around and will move the ball well against the Buffalo defense.
Miami at Detroit	DET -2 (43.5)	DET	O	Miami is on a roll, but Detroit has an elite offense and defense and is at home.
Dallas at Jacksonville	DAL -7.5 (45)	DAL	U	The chance of no Tony Romo is scary, but so is Jacksonville's defense against DeMarco Murray.
San Francisco at New Orleans	NO -6 (49)	NO	O	The Saints at home will be able to upend a reeling San Francisco team.
Tennessee at Baltimore	BAL -10 (44)	BAL	U	A two-win Tennessee team stands no chance against a surefire contender.
Pittsburgh at NY Jets	PIT -6 (46)	PIT	U	A quarterback issue in New York will only get worse with Pittsburgh in town.
Atlanta at Tampa Bay	ATL -3 (46)	ATL	O	See analysis below.
Denver at Oakland	DEN -11.5 (50)	DEN	O	See analysis below.
St. Louis at Arizona	ARI -7 (43)	STL	U	St. Louis has a way of keeping games close and just upended San Francisco.
NY Giants at Seattle	SEA -7.5 (44.5)	SEA	O	Seattle has been no sure thing at home this year but will be against an injured New York team.
Chicago at Green Bay	GB -7.5 (53.5)	GB	O	Green Bay had a week of rest to figure out Chicago's defense, which is scary.
Carolina at Philadelphia (Mon., Nov. 10)	PHI -7 (48)	CAR	U	With the sudden question mark under center for Philadelphia, this one defers to a Carolina team that is getting healthier.

Odds via Odds Shark as of 8 p.m. ET, Nov. 7.

Over/Under Lines to Bet

Atlanta (-3) at Tampa Bay

Over/Under: 46

USA TODAY Sports

Ugly football is often a breeding ground for a strong betting environment.

Think back to Week 3 of this season, when the Atlanta Falcons single-handedly blew past this very over/under mark with a 56-14 shellacking of the Tampa Bay Buccaneers.

Let's not pretend that Lovie Smith's miserable defense has done anything to suggest there is not another lopsided, high-scoring affair on the table, either. The Buccaneers have since allowed 24, 37, 48, 19 and 22 points, the latter two numbers coming against the miserable offenses of Minnesota and Cleveland, respectively.

Smith has inexplicably decided to go back to veteran Josh McCown under center, too, as noted by Ryan Edwards of The Drive on 104.3 The Fan:

But hey, on the off chance bettors out there are worried that the league's 31st-ranked defense somehow gets it together, keep in mind that since the win over Tampa Bay, the Atlanta defense has allowed 41, 30, 27, 29 and 22 points, the first number coming from the laughably bad Minnesota offense.

Atlanta ranks one spot better than the Buccaneers in the pass defense department, which is not saying much of anything at this point. But if bettors get to the final frame and are biting their nails that the over will not be covered, fret not, Atlanta cares for those bettors. Greg Auman of the Tampa Bay Times has the details:

Atlanta is the lesser of two inept teams and easily has the better quarterback, so anything short of a road victory will be a disappointment. Bettors can win in the process with the over, as there will be little defense on display Sunday. 

Prediction: Falcons 48, Buccaneers 30

Denver Broncos (-11.5) at Oakland Raiders

Over/Under: 50

USA TODAY Sports

It is only right that some semblance of doubt creeps into the minds of bettors when it comes to this line and over/under offering.

After all, in a year in which Seattle has lost at home and contenders such as San Francisco are erratic at best on a week-to-week basis, Oakland getting its first win of the season with Peyton Manning in town does not seem all that outlandish.

Then again this is Manning, who has one bad performance on the year, but still completes 67.3 percent of his passes and has 24 touchdowns to just five interceptions. Oh, and that bad performance came just last week in a loss to New England, so an angry Manning is one bettors should want to ride.

"The quarterback stinks, usually you're not going to win many games," said Manning, per STATS LLC on ESPN.com. "I don't make any excuses."

Fear not, though, as Oakland can and will do its fair share of scoring. The Broncos tout the league's best run defense, but partially because teams are too busy exploiting a shaky pass defense that ranks 24th in the league with an average of 254.0 yards allowed per game through the air. 

Oakland has no wins just yet, but rookie quarterback Derek Carr has been an encouraging sign for the future. He has quietly completed 60.7 percent of his passes for 1,711 yards and 11 touchdowns to seven interceptions. As Brad James points out, he is about as comfortable in the pocket as Manning thanks to his surroundings: 

In short, one of Sunday's more underrated matchups is an environment that should make bettors very comfortable with the over. Keep in mind that the Raiders have dropped 28 on San Diego this season and just last week put 24 on the Seahawks in Seattle.  

Manning is going to get his win, but Oakland will put things over the top in regards to the over/under. Be sure to take advantage.

Prediction: Broncos 35, Raiders 21

Note: Stats courtesy of NFL.com. Advanced metrics via Pro Football Focus (subscription required). Indianapolis, Minnesota, New England, San Diego, Washington, Houston on bye.