NFL Week 6 Picks: Teams That Will Win Weekend's Top Showdowns

Week 6 features several highly anticipated clashes, and the New England Patriots are one team that will win in big showdowns this weekend.

Only three undefeated teams remain after two went down last week. The Denver Broncos, the Kansas City Chiefs and the New Orleans Saints are all looking to stay perfect. On the other hand, four teams failed to get a win in the first five weeks.

There will be plenty to watch for this weekend. The San Francisco 49ers and the Arizona Cardinals will be battling for second place in the NFC West on Sunday, but that clash doesn't make the list of Week 6's top games.

Below is a full schedule for Week 6 along with teams that will win in big showdowns.

Green Bay Packers (at Baltimore Ravens)

Both teams need this game, but it will be the Green Bay Packers who come out on top. 

The Baltimore Ravens are in a three-way tie atop the AFC North. Although a loss won't ruin their chances of repeating as Super Bowl champions, they need to keep pace with the Cincinnati Bengals. Baltimore can't be looking ahead as it has three straight division games after this week.

The Ravens haven't scored more than 20 points in back-to-back weeks this season, so the offense may not be able to keep up with Aaron Rodgers.

Green Bay has alternated wins and losses this season. If that trend continues, it would be due for a loss.

On paper, this looks like a game Baltimore should win. The Ravens are 2-0 at home, and the Packers are 0-2 on the road. Green Bay has lost two contenders, so they are looking to show that they can compete with the best. 

The Packers rank fourth in passing and fifth in rushing, which is unusual for them. They have been able to be balanced on offense. Baltimore ranks 14th against the pass and 27th against the run, so Green Bay should be able to exploit the Ravens' weaknesses.

Green Bay had a bye two weeks ago to get healthy and prepare. The Packers were dominant against the Detroit Lions last week, and they will keep their momentum as they head to Baltimore.

New England Patriots (vs. New Orleans Saints)

There is no question as to what game is the biggest matchup of the weekend. The unbeaten New Orleans Saints will head to Foxboro to take on the 4-1 New England Patriots.

It has been a great turnaround in New Orleans as Sean Payton has helped the offense. The Saints have passed every test to date, but they picked the wrong time to visit Tom Brady and the Patriots.

New England's passing attack ranks 21st in the NFL. That's not what many expect out of a Brady-led squad. However, this could be a huge week for the quarterback. Receiver Danny Amendola returned to action last week, and tight end Rob Gronkowski could make his season debut this weekend.

Albert Breer of NFL.com confirmed that Gronkowski is expected to play on Sunday. If so, Brady will finally be able to have reliable targets.

New Orleans has won three games, including both road games, by one possession this year. After the Patriots lost last week, most expect Brady to bounce back. New England has lost back-to-back games only twice in the last three seasons.

Brady's streak of throwing at least one touchdown in 52 straight games came to an end last week. Instead of potentially tying Drew Brees' NFL record of 54 consecutive games, Brady will look to start a new streak.

The weather shouldn't be as bad as it was last week, so look for Brady to utilize his improved receiving corps. 

Indianapolis Colts (at San Diego Chargers)

While the other two showdowns each feature two premier contenders, this game will be interesting as the San Diego Chargers have turned some heads this year.

San Diego has alternated wins and losses this season, and it is due for a win this week. The Chargers have lost three games by a combined 16 points. Although they are 2-3, they could easily be 4-1.

However, the Chargers will be hosting one of the league's hottest teams. The Indianapolis Colts are 3-0 since acquiring Trent Richardson, and they are playing with a lot of confidence. They are 2-0 on the road and have won by a combined total of 64-10.

The Chargers rank 24th against the run. Richardson has averaged 50 yards per game and three yards per carry with the Colts. This will be a strong week for him as he will now be expected to carry the load after it was announced that Ahmad Bradshaw will miss the rest of the season with a neck injury, according to ProFootballTalk.com.

Indianapolis has had one of the league's top running games this season, and Andrew Luck can beat any team with his arm. Wideout T.Y. Hilton had a huge game against arguably the best pass defense in the league last year. Hilton had 140 yards and two touchdowns against the Seattle Seahawks last week.

The Colts have had a strong offense for much of the past 15 years, but it's the defense that is making noise. They are physical on defense and make it tough for opposing teams to get anything going.

This Monday Night Football game will be fun to watch, but look for the Colts to continue their surge. 

*All stats are courtesy of NFL.com