Michigan vs Notre Dame Betting Odds Preview, Prediction

The Michigan Wolverines are 0-4 SU and 0-3-1 ATS in their last four games against ranked opponents, and the Wolverines get their first chance this season to knock off a ranked team when they host the No. 14 Notre Dame Fighting Irish on Saturday night at the Big House.

As of early this week, most college football betting shops tracked by OddsShark.com were listing the Wolverines as a four-point favorite over the Fighting Irish, with the OVER/UNDER set at 52 points for the contest.

Michigan, ranked No. 17 in this week's polls, began its 2013 season last weekend with an easy 59-9 victory at home over Central Michigan, covering the spread as big 31-point favorites at the sportsbooks.

The Wolverines scored two minutes into the game against Central Michigan on a blocked punt return and never looked back, eventually racking up 463 yards of offense, 242 yards on the ground, while holding the Chippewas to 210 total yards.

Notre Dame, meanwhile, began its season with a 28-6 victory over the Temple Owls last week, but couldn't cover the spread as 27-point home chalk at the sportsbooks. The Fighting Irish rang up 543 yards on offense, with 346 of those yards coming on just 16 completions by quarterback Tommy Rees.

Notre Dame led 21-6 at the half in that contest and 28-6 after three quarters, but couldn't come up with the one additional score that would have made winners out of its financial backers on the day.

During its run at the BCS national championship last year Notre Dame went 4-1 SU and 3-1-1 ATS against ranked foes.

Michigan had won three games in a row in this rivalry until last year, when the Fighting Irish won an ugly affair in South Bend by a final score of 13-6. However, before that the point spread underdog had won the previous four games in this series outright.

Overall, Michigan has won 15 straight at home, going 10-5 ATS.

Saturday night's showdown will be televised live by ESPN beginning at 8 pm ET.

Computer Prediction: 36-28 Michigan, from Odds Shark Computer