MLB Picks: Los Angeles Angels vs. Chicago Cubs

The Los Angeles Angels are 80-44 in interleague play since 2007, which is important to consider when making your MLB picks on Wednesday as they close out a two-game series with the Chicago Cubs at Wrigley Field.

Courtesy of SBR Forum, the Angels are minus-122 road favorites in the pro baseball odds, with the total sitting at 7.5 in the market.

Let's take a closer look at this matchup from a betting perspective, while offering up a prediction along the way.

Los Angeles Angels

The Los Angeles Angels had their two-game winning streak snapped on Tuesday night, suffering a 7-2 series-opening loss to the Chicago Cubs as minus-138 road favorites.

Angels starting pitcher C.J. Wilson is 4-3 with a 4.64 ERA in nine road starts this season.  

Chicago Cubs

The Chicago Cubs are 13-6 against American League opponents in 2013, which includes wins in seven of their last eight games at home in that situation.

Cubs starting pitcher Jeff Samardzija is 2-3 with a 4.47 ERA in nine starts at Wrigley Field, with opposing batters hitting .284 against him. 

Prediction

I'm going to recommend that readers back the Los Angeles Angels as one of their MLB picks on Wednesday, as they've won eight of C.J. Wilson's last 10 starts as a road favorite of minus-110 to minus-150.

MLB Pick: Los Angeles Angels minus-122

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