NCAA Brackets 2013: Favorites in Danger of Falling in Round of 64

Not a year goes by where we don't see a few upsets in the Round of 64 in the NCAA tournament. 

Last year, we saw No. 15 seed Lehigh knock out Duke early, while No. 15 seed Norfolk State shocked Missouri and No. 13 seed Ohio battled past Michigan.

Don't expect anything to change in the 2013 NCAA tournament. There is bound to be an upset practically nobody saw coming. 

Here's a look at some upsets I see on the horizon (upsets based on VegasInsider.com's odds/probable odds, not seeds).

No. 6 Memphis (vs. No. 16 St. Mary's/Middle Tennessee)

Spread: N/A

Memphis plays the winner of St. Mary's and Middle Tennessee. If Middle Tennessee somehow emerges from the first round, I could see Memphis beating the Blue Raiders.

But St. Mary's will likely be the team that advances, and that would spell trouble for the Tigers.

Memphis may not have the offense to keep up with St. Mary's. While the Tigers rank 46th in offensive efficiency, the Gaels ranks fourth in the category. The Tigers also rank 220th in turnovers per possession this season, and they could have a tough time on the glass against St. Mary's (ranked fifth in the nation in rebounding rate).

Prediction: Memphis Loses

No. 11 Minnesota (vs. No. 6 UCLA)

Spread: -3

A lot is being made of Jordan Adams' broken foot, and for good reason. The freshman guard was the Bruins' second-leading scorer this season.

But UCLA still has the talent to put enough points up on the board against Minnesota in the Round of 64, ranging from star Shabazz Muhammad to fellow freshman Kyle Anderson to junior Travis Wear.

Keep in mind, Minnesota ranks 72nd in the country in defensive efficiency this season. The Golden Gophers also rank 62nd in offensive efficiency. 

The biggest thing for the Bruins will be playing defense. They rank 138th in opponents' field-goal percentage this season, and 106th in defensive efficiency. 

In the end, I see UCLA getting it done.

Prediction: Minnesota Loses

No. 9 Missouri (vs. No. 8 Colorado State)

Spread: -3

Colorado State is a veteran team that made it to the NCAA tournament last season. The Rams also rank 11th in the nation in offensive efficiency.

Missouri does hold the advantage on the defensive end, but Colorado State ranks first in the nation in rebounding rate (led by Colton Iverson and Pierce Hornung), which could pose a major problem for the Tigers.

On top of that, Colorado State played a tougher overall schedule this season (ranked 34th in strength of schedule).

Prediction: Missouri Loses

Don't forget to print out your bracket and follow along with the live bracket. Make your picks for the 2013 NCAA tournament here with the Bracket Challenge Game.

All stats via ESPN.com and TeamRankings.com.