Fantasy NFL Rumors: Brock Purdy Expected to Start for 49ers vs. Bills amid Injury

San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's Adam Schefter.

Purdy was limited in practice on Wednesday and Thursday before being a full participant Friday. The Niners listed him as questionable in their injury report. He previously sat out Week 12 with a shoulder injury, marking the first missed game of his NFL career.

The injury occurred during a Week 11 contest against the Seattle Seahawks on Nov. 22. Purdy finished out the game but recorded a season-low 5.68 yards per pass attempt in the loss.

Purdy was limited in practice the following week. He ended up leaving a session early and eventually ruled out for Week 12.

Niners head coach Kyle Shanahan said that Purdy had left practice after his shoulder pain "started up."

"So we had to shut him down, and so I really don't know what to think of it," Shanahan said. "The MRI doesn't look like that, so it should be alright, but the way it responded this week, it's really up in the air for next week."

Fox Sports' Jay Glazer reported two days later that the 49ers had undergone a second MRI on Purdy's shoulder, but that the scan "didn't really show anything else."

With Brandon Allen starting in Purdy's place during Week 12, San Francisco was held to a season-low 10 points and 44 rushing yards in a blowout loss to the Packers.

Purdy's availability going forward will be crucial to the 49ers' hopes of sneaking into the playoffs as a Wild Card.