Houston Astros 2018 schedule
April
Tickets| Apr 28 | Athletics | 11:10 PM UTC | |
| Apr 1 | @Rangers | W | 8–2 |
| Apr 8 | Padres | W | 4–1 |
| Apr 14 | Rangers | L | 6–5 |
| Apr 14 | Rangers | W | 3–2 |
| Apr 25 | Angels | 6:10 PM UTC | |
| Apr 29 | Athletics | 6:10 PM UTC | |
| Apr 19 | @Mariners | W | 7–1 |
| Apr 4 | Orioles | W | 10–6 |
| Apr 28 | Athletics | 12:10 AM UTC | |
| Apr 25 | Angels | 12:10 AM UTC | |
| Apr 24 | Angels | 12:10 AM UTC | |
| Apr 4 | Orioles | W | 3–2 |
| Apr 11 | @Twins | L | 9–8 |
| Apr 7 | Padres | L | 4–1 |
| Apr 7 | Padres | W | 1–0 |
| Apr 11 | @Twins | L | 4–1 |
| Apr 2 | Orioles | W | 6–1 |
| Apr 22 | @White Sox | 6:10 PM UTC | |
| Apr 21 | @White Sox | 11:10 PM UTC | |
| Apr 21 | @White Sox | W | 10–0 |
| Apr 10 | @Twins | W | 2–0 |
| Apr 18 | @Mariners | W | 4–1 |
| Apr 19 | @Mariners | W | 9–2 |
| Apr 17 | @Mariners | L | 2–1 |
| Apr 16 | Rangers | L | 3–1 |