Not many players receive that title. Most of the ones that do come from superior stock.
Take Peyton Manning for example.
His was destined for greatness. His double helix is in the shape of a football. While in the womb, he watched game film of various defensive schemes.
On the other hand, some players don't have that superior pedigree. They have had to work a little harder than others. Perhaps they were "too short" or "too slow" to play in the NFL.
But not only did these players have the wherewithal to make it into the NFL, they also pushed themselves into superstar status.