They've risen from the ashes of last year's travesty of a season (all you need to know is that they started the 2010 season with five straight losses) and put together a team that many consider a legitimate contender in the NFC.
Because their quarterback situation is healthy, their running game is productive and their defense is dependable.
The latest playoff predictor on ESPN.com has San Francisco clinching the No. 2 seed in the NFC, earning a first-round bye and having home-field advantage against any team not named Green Bay.
If New Orleans is the No. 3 seed (which is just about a lock) Drew Brees & Company will have to travel to Candlestick Park. Brees will break Marino's single-season record of 5,084 passing yards; but the Saints don't travel well, losing road games against St. Louis (what?) and Tampa Bay (the Jaguars beat them!).
That means that San Francisco has a really good shot at playing Green Bay in the NFC title game.
And I think San Francisco has built the team with the best chance of beating the seemingly invincible Packers. How?
Join me as I show you why San Francisco not only matches up well, but should be favorites to win against Green Bay.