Week 15 spawns the beginning of the playoffs for fantasy owners fortunate enough to still be alive.
Due to some serious injuries to stars such as DeMarco Murray and Greg Jennings, owners are scrambling for viable replacements.
Some players that belong on the waiver wire would be fantastic starts this week due to terrific matchups or recent hot play.
Other players who normally belong in fantasy lineups should be left on the bench thanks to difficult matchups or injury concerns.
Here are 10 players you should start or sit in this crucial week of fantasy football.
Tim Tebow could be a useful start this week for fantasy owners.
The Florida product faces a terrible Patriots secondary this week, and he should be able to take advantage of the great matchup.
The Broncos will likely be behind early against a strong New England squad. This will force Tebow and Company to air it out from the start.
The Heisman Trophy winner will rack up the yardage, as well as a few scores for fantasy owners.
Projection: 232 passing yards, one passing touchdown, one interception, 32 rushing yards, one rushing touchdown, 20 fantasy points
Michael Vick has been a disappointment to fantasy owners all season, and his struggles are likely to continue this week.
Vick will be too hurt to avoid a ferocious Gang Green pass rush, and he will be forced into several key mistakes.
Facing the best cornerback duo in the league doesn't help either.
Projection: 237 passing yards, one touchdown, two interceptions, 23 rushing yards, 11 fantasy points
Shonn Greene is a terrific start this week in Philadelphia.
The Jets running back has been on fire lately, and he has exploded for 217 yards and four touchdowns over the last two games.
The Iowa product continues to receive 20-plus touches a game as New York's feature back, and he will likely see even more this week. Rex Ryan would be smart to attack the ground against a weak Philadelphia run defense.
This terrific matchup will lead to another fantastic game for the tough Greene.
Projection: 24 carries, 88 yards, one touchdown, two receptions, 14 yards, 15 fantasy points
Mendenhall has been inconsistent all season, and a playoff matchup with the 49ers will once again disappoint his fantasy owners.
The Illinois product has struggled for most of the season even as the Steelers' feature back.
The 49ers rank first in the league in run defense, and they have not allowed a rushing touchdown all season.
Mendenhall should be a no-go in the majority of leagues this week.
Projection: 13 carries, 41 yards, one reception, eight yards, four fantasy points
Santana Moss returned to fantasy relevance after a superb outing in New England last week.
The former Pro Bowl wideout is guaranteed to receive a lot of targets this Sunday, as he should be able to find room in a potentially high-scoring game.
Projection: six receptions, 71 yards, one touchdown, 13 fantasy points
Santonio Holmes has underachieved this season for fantasy owners.
The Jets wideout came into the season as a solid No. 2 receiving option in standard leagues, but he has performed below those standards.
The former Super Bowl MVP continues to struggles in terms of yardage, with his only production coming from finding pay dirt.
This week, against elite cornerback Nnamdi Asomugha and a terrific Eagles secondary, Holmes is unlikely to score.
Projection: three catches, 32 yards, three fantasy points
Brandon Pettigrew has a terrific matchup this week.
Pettigrew continues to receive a boatload of targets from Detroit quarterback Matthew Stafford, so he should be able to produce for owners this week.
Projection: five catches, 47 yards, one touchdown, 10 fantasy points
Vernon Davis has not performed up to the level fantasy owners expected after they drafted him so high last summer.
The 49ers tight end has had three straight games of under 40 receiving yards and no touchdowns.
Davis now faces a very tough matchup with a stifling Steelers defense this Sunday.
The former fantasy star will once again disappoint, and perform below his talent level.
Projection: two receptions, 23 yards, two fantasy points
For fantasy owners looking for a solid defense off the waiver wire, the Cardinals are a terrific option.
Arizona faces a terrific matchup against an awful Browns offense that could be without their starting quarterback.
The Cardinals defense should dominate Cleveland all game long, forcing turnovers and allowing just a few yards and points.
Projection: 223 yards allowed, 12 points allowed, two turnovers
The Broncos defense deserves as much credit for Denver's recent surge as Tim Tebow does.
The unit has been a viable option for fantasy owners recently, as they have held four of their last five opponents to 13 points or fewer.
However, Denver's defense faces a very difficult matchup with a prolific Patriots offense this week, and they should struggle.
Tom Brady and Company will drive down the field at will and rack up the points in Mile High come Sunday.
Projection: 401 yards allowed, 31 points allowed