To pull off the road upset with AJ Feeley filling in for Sam Bradford at quarterback, they'll need to make these changes at the half.
5. Take chances downfield.
At 2-9, the Rams have nothing to lose here. The ground game has struggled, and the Rams can't be afraid to throw downfield. Brandon Lloyd wasn't even targeted until the 2:00 warning had already passed.
4. Take advantage of Patrick Willis' absence.
Injuries are part of football, and the 49ers will be playing without one of the top defensive players in the entire NFL after he went out with a gimpy hamstring. The Rams need to figure out ways to take advantage of his absence, whether it be passes over the middle or running at his replacement.
3. Limit costly giveaways.
The Rams were lucky to hold San Francisco to a field goal after turning the ball over in their own red zone. The St. Louis offense isn't good enough to win if any others happen.
2. Get pressure on Alex Smith.
St. Louis has done a nice job of bending without breaking by letting the 49ers move the ball between the 20s but tightening up deep in their own territory. However, the Rams have let Smith become too comfortable in the pocket, as he's been in a good rhythm hitting his targets.
1. Protect Feeley.
Feeley hasn't had much time to throw. He's only been sacked twice, but if the Rams are to get going offensively, he'll need more time to operate.