Coming off the back of a 2-1 victory over a floundering Chelsea team last Sunday at Stamford Bridge, Liverpool welcome rampant league leaders Manchester City to Anfield in what will certainly provide the sternest test of Kenny Dalglish's rebuild team to date.
City have been in incredible form in the league this season, dropping only two points and sweeping aside opponent after opponent with some of the best attacking football seen in the Premier League since the Arsenal invincibles.
Liverpool, for their part, are in the midst of a nine match unbeaten run and have beaten Arsenal and Chelsea away from home this season and drawn at home to Manchester United in a match they deserved to win. Liverpool have raised their performances against the top teams but struggled to beat the lesser teams. Recent home draws with Norwich and Swansea have shown that they still have a lot of work to do if they wish to mount a serious challenge for a top four position.
Liverpool are certainly capable of winning this match but they must be smart tactically. They need to play a certain way to maximize their chances and marginalize City's effectiveness.
The Reds recent record against City at Anfield is certainly impressive but this Manchester City team, with Silva, Aguero, Balotelli and Dzeko all in fantastic form this season, are a much different proposition.
Liverpool must stop City's key men and make sure that their own key men perform at the height of their ability if they are to win this match.
With that in mind, here are five keys to victory for the Reds in the showcase match of this Premier League weekend.