After starting 0-3 to begin the season, the Chiefs are on a three-game winning streak. The Chargers were 4-1 heading into last week's meeting with the New York Jets, but shot themselves in the foot with some costly turnovers and lost the game.
A tie for first place in the division is on the line for the Chiefs if they win, but if the Chargers win they would be in sole possession of first place with a 5-2 record.
Let's take a look at all you need to know about this exciting AFC West matchup, which will take place on Monday night football, Halloween style.
Where: Arrowhead Stadium, Kansas City, MO
When: Monday, Oct. 31 at 8:30 p.m. EDT
Spread: Chargers -4
The Chargers are four points favorites this week and it's entirely possible they could beat the Chiefs by at least a touchdown this week.
Chargers quarterback Philip Rivers will be eager to bounce back after a poor performance against the Jets last week.
If I bet on this game, I'd take the Chargers as four point favorites. A win puts them in good shape in the AFC West, which they'll need with a Week 9 matchup against the Green Bay Packers.
Chargers Key Injuries
Questionable: Mike Tolbert (hamstring/hand)
Probable: Antonio Gates (foot)
Chiefs Key Injuries:
Big Fantasy Plays
QB Philip Rivers (SD) - Philip Rivers is one of the top quarterbacks in the NFL, and after a poor game last week against the Jets, Rivers will have a big bounce back game against the Chiefs in Week 8.
With top pass-catchers Vincent Jackson and Antonio Gates ready to go and healthy this week, Rivers will have a very good chance to pass for 300-plus yards.
WR Dwayne Bowe (KC) - Dwayne Bowe is a great deep threat wide receiver and is Matt Cassel's favorite and most reliable target.
Bowe is averaging 94.5 yards receiving in his last four games, and has four touchdown catches in the same span.
He is a very smart and reliable fantasy play this week.
Keys to a Chargers Win
The San Diego Chargers cannot turn the ball over. They must win the turnover battle against a Chiefs team starting to find success in the running game.
Offensively, the Chargers must get Philip Rivers going early, and if the passing attack is successful early on that will open up the running game.
Having running back Ryan Mathews get a lot of touches in both the rushing and passing games will be key as well. The Chargers would be smart to utilize his playmaking ability.
Keys to a Chiefs Win
The Kansas City Chiefs must start the game off with some points because their offense is not explosive enough to beat the Chargers in a shootout.
If the Chiefs can force the Chargers to throw the ball because they are facing an early deficit, they can sit back and force Rivers into making some bad throws.
Rivers has nine interceptions already this season, and the athletic Chiefs defense could change the momentum of the game with a key turnover.
Chargers over Chiefs 24-17