Andrew Luck is a safe bet to be the No. 1 overall pick in the 2012 NFL Draft. He has the size, the skill, and the pedigree to be a star at the next level.
Jim Harbaugh, his coach of three seasons, has turned around the San Francisco 49ers, so it is safe to say he has been raised in a system that will make his NFL transition relatively easy.
The same cannot be said for many other big-time NCAA quarterbacks. Here are five players who will prove to be busts at the next level.