Fortunately for you, there are a few guys who have good match-ups this week and could be valuable short-term solutions.
Keep in mind, these aren't guys you want to start all year, but they'll be decent stopgaps for one week.
Let's take a look at three waiver-wire quarterbacks with good match-ups this week.
Andy Dalton, Cincinnati Bengals
Dalton has developed good chemistry with fellow rookie A.J. Green. That connection could be a part of the Bengals offense for years to come.
This week, Green and Dalton get to go to work against the Indianapolis Colts defense.
The Colts allow an average of more than 250 yards per game to opposing quarterbacks and only have three interceptions on the season.
Dalton should be able to have a pretty decent game as long as his offensive line limits the number of sacks Dwight Freeney and Robert Mathis get.
Colt McCoy, Cleveland Browns
McCoy and the Browns have been somewhat disappointing this year.
That's in large part due to his lack of decent receivers and Peyton Hillis' ineffectiveness.
He's not going to be great this weekend, but the Oakland Raiders allow nearly 300 yards per game through the air, so he has a chance.
He should find a few openings and contribute a couple touchdown passes to your fantasy team.
Only start him if your starter is on a bye week though, because the rest of the Browns offense is terrible.
Mark Sanchez, New York Jets
Sanchez hasn't been good this year, but if there's going to be a week that he has decent numbers, it'll be this week.
The Miami Dolphins are giving up the second most passing yards in the NFL this season, with 307 yards allowed per game.
The Jets should have no trouble controlling the ball offensively, and Sanchez should actually put up some decent numbers.
Santonio Holmes and Plaxico Burress should also have their best games of the season to date.