Roberto Mancini's men will be eager to show that their 2-2 draw at Craven Cottage was little more than a temporary blip against a resilient Fulham team.
The Citizens currently rest second in the Premier League, however they are the first to blink against cross city rivals Manchester United.
Everton on the other hand are fighting a battle of their own. Having lost Mikel Arteta at the last possible moment, the Toffees have had to adapt to Premier League life without their star player.
So far, David Moyes' men have continued to outperform the investment put into the squad, but against Manchester City they will face their biggest test of the season to date.
The fixture is one of the oldest, and tightly contested, in Premier League history and it has unsurprisingly yielded some shock statistics. Read on to find out more...