Injuries are bound to happen in the rigorous NFL, but many teams just hope they don't happen to star players.
Unfortunately they do and they definitely have thus far in the season.
Here are a few teams that will definitely struggle with their recent injury departures, even if they aren't season ending.
It was clear through just two games this season that the Kansas City Chiefs weren't the fast-paced, explosive squad that won the AFC West just a season ago.
That was with Jamaal Charles.
Now that Charles has been diagnosed with a torn ACL, the Chiefs may be in the running for Andrew Luck in next year's draft.
The Cowboys will have to deal with a duo of injuries, unfortunately to their top two players.
We all know Tony Romo fractured some ribs and had a punctured lung, however he is only questionable heading into Week 3.
But, top wideout Miles Austin suffered a hamstring injury, which could hold him out until mid-October.
As many know, hamstring injuries can be nagging and more importantly lagging, never really healing until after the season.
After beginning the year 1-1 in the dreadful NFC West, the 49ers could be in jeopardy of tanking after their most recent loss.
Braylon Edwards suffered a meniscus tear in his knee and is expected to be out for weeks to come.
One of the few threats on the outside for Alex Smith, it is not positive looking forward.