Final score: 35-21 New England Patriots
Brady's 517 yards last week was the fifth most passing yards in a game in the history of the NFL. However, the Chargers held Brady to just 19 completions and 159 yards in their 2010 matchup.
In last year's matchup, the Patriots narrowly escaped San Diego with a 23-20 victory over the Chargers. Kris Brown clanged a 50-yard field goal attempt off of the right upright in the waning seconds. The field goal would have sent the game into overtime.
The Chargers held the Patriots to just 179 yards of total offense in the game. As the game wore on, Philip Rivers became unstoppable, ending the game with 336 yards and completing pass after pass in the fourth quarter.
In the 2011 iteration of the Chargers-Patriots, the Chargers hope to hold Brady to another subpar game. In their first game of the season, the Chargers were able to hold Donovan McNabb to just seven completions and 39 yards in their first game of the season.
It will be interesting to see how the Patriots' high-powered offense will perform again the Chargers, whose defense held the Vikings to the lowest yardage total out of any team in the league last week.
Both teams have dreams of the Super Bowl this year and this game will be a solid measuring stick to see where they presently stand.
The weather in Foxboro is expected to be around 63 degrees at kickoff and there is a 10 percent chance of rain. Kickoff is at 4:15 p.m. EST and the game will be broadcast on CBS.
Feel free to comment with feedback or questions below. Most questions will be incorporated into the live blog and answered as the game goes on.