This is a very important game for the Rams not only because it will be their head coach Steve Spagnuolo's return to New York, but also because a 0-2 start makes the road to the playoffs even more rigorous.
The Rams will have their hands full playing against the Giants this week. Both teams are a bit banged up, but it seems safe to say that the Rams suffered bigger losses in Week 1. The New York Giants are playoff contenders every year, and they should be favored over St. Louis.
Five things really popped out to me in this game as serious advantages or disadvantages. Factors such as injuries aren't listed because they will plague both teams. With that said, here are some key factors to keep an eye out for on Monday Night Football.