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Savvy and mobile veteran striker Marko Pantelic will provide the greatest danger to Arsenal during their two matches with the Greek giants.
The former Ajax front man has excellent movement and is a sharp finisher. Thomas Vermaelen will be key to controlling Pantelic.
The Serbian's prowess in the air cannot be underestimated and shadowing his clever runs will be crucial for Vermaelen.
Arsenal fans may not consider facing former Liverpool flop Albert Riera a particularly daunting task. But the Spanish winger is a capable wide attacker when on form.
Riera can deliver an excellent cross and could link up well with Pantelic to expose one of Arsenal's most frequent failings. He can also chip in with goals from some well-timed runs and the Gunners cannot afford to overlook the rejuvenated Spaniard.
Arsenal has drawn an awkward looking group. They face experienced and determined squads offering plenty of quality.
All three away fixtures will send Arsene Wenger's crop of youngsters to intimidating venues. Arsenal's starlets will be forced to grow up fast and prove their strength and depth.