Not only was this one of the greatest game-winning drives in NFL history, but it was one of the best comebacks ever to occur in postseason contest.
The Colts had lost two previous playoff encounters with the Patriots. Both of those games were in chilly Foxborough. For the 2006 AFC Championship Game, Indy would have the luxury of playing in the RCA Dome on a dry and fast surface and getting to play before a deafening and supporting crowd.
Those Colt fans were silenced early when New England jumped out to a 21-3 lead.
The deficit shrunk from 18 and eventually became a tie score with an Adam Vinatieri field goal. Pats kicker Stephen Gostkowski answered with a 43-yard boot to put Bill Belichick's club up 34-31.
After trading defensive stops, the Colts gained possession with slightly more than two minutes to go. Peyton Manning, overcoming an injury to the thumb on his throwing hand and trying to dispel the New England demons, moved his offense 70 yards in the span of 19 seconds.
At the Pats' 3, running back Joseph Addai's touchdown run with one minute left gave Indy its first lead. Tom Brady tried to counter for the Patriots, but a Marlin Jackson interception sealed the Colts' AFC title – a win that would propel them to the Super Bowl XLI crown.
Highlights of the game begin at the 6:41 mark of the video.