New Orleans Saints' defensive end Will Smith (above) and running back Duece McAllister were named as was Texans' long-snapper Bryan Pittman. It is believed that there are at least two more Saints that are on the list but their names have not been released yet.
The number was initially reported to be 6-10 players but according to New Orleans radio station WWL AM, that number is now hovering around 15. The reporter who broke the story, Josina Anderson spoke on the radio station earlier today.
It is believed that the other players who failed the test are not big names like Smith and McAllister are. Both players will play against the San Diego Chargers in London this weekend.
Attorney David Cornwell told ESPN's Chris Mortensen that he had been retained by a number of players to represent them in the NFL appeals process but the attorney wouldn't put a number on the players nor mention any names.
Both McAllister and Smith practiced in London this morning and the Saints' spokesman, Greg Bensel wouldn't comment on the failed test results saying that it was a league matter.
NFL spokesman Micheal Signora said that the NFL would not comment on any reports.
Both are in London for the game on Sunday.
The agents for Smith and McAllister wouldn't return calls from the media but it appears that Pittman will appeal.
The players could each face a four game suspension and with Reggie Bush out and the Saints' defense on the fritz, that would send the Black and Gold even deeper into the divisional basement.
Last year, former Saints' defensive tackle Hollis Thomas failed a drug test and was suspended for the mandatory four games although his suspension was because of an asthma medicine he had taken, the banned substance that Smith and McAllister consumed is known as Bumetanide.
Bumetanide is a drug belonging to a group of medicines called loop diuretics or "water pills." Its uses include the treatment of swelling caused by medical conditions such as congestive heart failure, liver disease and kidney disease, according to Fox-31. It also decreases the amount of water retained in the body by increasing urination. It causes the kidneys to get rid of unneeded water and salt from the body into the urine, helping the user shed their body fat.
Many of the players tested positive for Bumetanide but others tested positive for a drug that works similarly.
Last year we had Spygate, now its WaterPillGate, what's next?