Game 1 starts at 8 PM Eastern for Boston fans and 5 PM Pacific time for Vancouver fans.
It will be televised nationally on NBC for American viewers, and on CBC's Hockey Night in Canada.
Will the Vancouver Canucks finally win a Stanley Cup for the first time in their 40-year franchise history?
Which Vezina Trophy-nominated goalie, Tim Thomas or Roberto Luongo, will come out on top?
Will Norris trophy nominated Zdeno Chara of the Bruins be able to stop Daniel and Henrik Sedin, the 2010 and 2011 Art Ross trophy winners?
We'll find out starting tonight.
Throughout the day, I'll update you with the latest news and storylines coming out of Vancouver on game day.