San Francisco (2-1) at New Orleans (1-2) Sunday 1:00pm FOX
This is a huge game for J.T. O'Sullivan and his 49ers.
After an impressive and surprising start, the 49ers are tied with the Cardinals atop the NFC West.
O'Sullivan has outperformed all expectations, and is going into his first big road game outside of his division.
The Saints have lost two close games in the last two weeks, with the Redskins coming back to beat them, and their own comeback attempt coming up short in Denver last weekend.
If the Saints are going to keep pace with the rest of their division, they need a victory in this game. It will not come easy, though, as the 49ers continue to be one of the biggest surprises in the league this year.
New Orleans 21, San Francisco 17.
Arizona (2-1) at New York Jets (1-2) Sunday 1:00pm FOX
This is a big game that will likely fly under the radar on a big weekend in the NFL.
The Cardinals are in first place in the NFC West, a sentence that has not been uttered in week four in a long time.
Kurt Warner has all but silenced the critics who challenged the call to make him the starter over troubled youngster Matt Leinart.
With the receiving corps of the Cardinals, the Jets’ secondary will be tested all day long.
The Arizona offensive line will be key in allowing Warner time to throw to these weapons.
Brett Favre and the Jets will be looking to rebound after a big loss on Monday Night Football last week in San Diego.
If the Jets slip to 1-3, Favre may feel his first real dose of New York tabloid pressure. Arizona 21, Jets 20.
Green Bay (2-1) at Tampa Bay (2-1) Sunday 1:00pm FOX
Green Bay will be looking to return to their winning ways under new quarterback Aaron Rodgers after losing to the Cowboys last week.
Tampa Bay has a chance to stay tied atop the NFC South standings, as the other two teams they are tied with, Atlanta and Carolina, are facing each other.
The Bucs will need to establish a running game that they completely abandoned last week, rushing only 17 times in their overtime victory in Chicago.
QB Brian Griese threw the ball 67 times last week, completing 38 of those attempts for two touchdowns and three interceptions.
The Packers can extend their NFC North lead with a win, pulling away early in the year.
Packers 20, Bucs 16.
Minnesota (1-2) at Tennessee (3-0) Sunday 1:00pm FOX
This is a close second for my Game of the Week pick. This is a huge match-up for this time of year.
Minnesota finally showed up for a game last week, knocking off the Panthers at home.
The Titans are one of only six remaining undefeated teams in the NFL. With the struggles in Indianapolis, the Titans are now the favorites to win the AFC South after an impressive start to the season.
Although they are without QB Vince Young, the Titans offense hasn’t missed a beat, with Kerry Collins filling in nicely and rookie running back Chris Johnson coming up big thus far.
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