The Titans have dropped five straight while doing the quarterback shuffle due to injuries to two of their three quarterbacks.
The Colts have been on a downward spiral due to sloppy play by Peyton Manning, who has thrown enough interceptions for a season in his past four games; Manning, however, has had the Colts right in the game near the end in a couple of the losses, something the Titans have not done.
Luckily, the Titans have had some success creating turnovers this year, especially by the way pf interceptions, so they may get some big plays from playmakers like Alterraun Verner and Michael Griffin.
Then again, Manning could get back in motion against a risk-taking defense that has allowed some big plays this year, through the air and on the ground.
There is a good chance Titans Head Coach Jeff Fisher will have the team come out and try to pass the ball. That could get some heat out of the box for Chris Johnson if quarterback Kerry Collins can have a good game; however, Johnson has been less than stellar since the 10-0 start to the 2008 season.
Collins has been struggling with his accuracy of late, especially on balls over fifteen yards, as he has the tendency to throw the ball too short, allowing defenders to have a shot at making a play on the ball.
With Manning and Collins both having some downtime in recent weeks, the running games have also struggled. The Colts' running game hasn't really been there at all this year, but the Titans have had some success, at times, on the ground.
The biggest problem is that without the threat of a pass, even a defense as sloppy as the Colts will be able to slow down Johnson by plugging all the gaps.
The Titans have the defensive edge in this game, as their line has created an abundance of sacks this year, and the Colts offensive line has been exposed a couple of times this year. Titans defensive coordinator Chuck Cecil and defensive line coach Jim Washburn should have the defensive line ready to get after Manning and let him have a long night after a short week.
In the end, this game could go either way, but the Titans are playing at home, outside in the cold and not in the dome the Colts are used to.
With that said, I am going to actually pick the Titans in this game.
Tennessee Titans 19 Indianapolis Colts 13