Hargreaves leaving the pitch after acquiring a left hamstring injury.
Owen Hargreaves's first start in over two years was cut short by another injury.
With injuries hampering the Red Devil squad, Ferguson made the decision to start Hargreaves in the midfield against Wolverhampton Wanderers.
However, just five minutes into the first half, Hargreaves limped off with a left hamstring injury.
He was replaced by Bebe.
Hargreaves has been hampered by numerous injuries, the most significant of which has been tendonitis in the knee.