NFL Week 6 Picks: Predicting the Upset Locks of the Week

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NFL Week 6 Picks: Predicting the Upset Locks of the Week
Jamie Sabau/Getty Images

In Week Five, the NFL saw four outrageous upsets from teams that entered their games as underdogs of more than a touchdown.

The Tampa Bay Buccaneers defeated the Cincinnati Bengals on the road, 24-21, despite being 6.5-point underdogs.

The Arizona Cardinals defeated the New Orleans Saints at home, 30-20, as seven-point underdogs.

The Oakland Raiders defeated the San Diego Chargers in Oakland, 35-27, as seven-point underdogs.

And finally, the Tennessee Titans traveled to Dallas as seven-point underdogs and upset the Cowboys, 34-27.

In the NFL, the saying "Any Given Sunday" is observable each and every week, which is a pretty self-fulfilling way to examine the veracity of the term.

So here is a look at how the term will be fulfilled this weekend with five upsets sure to shock the NFL. The picks are listed in order from smallest underdog to largest underdog in Week Six.

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