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Where They Stand Now: The Colts sit seventh in my rankings, having fallen from the top spot with last week's loss to the Houston Texans.
Why Their Matchup is Favorable: The Colts play the New York Giants, a balanced offensive team. The Giants' defensive line loves to rush the passer, but Peyton Manning loves it when defenses blitz. The Giants' linebackers don't have the speed or skill to defend the Colts' quick pass offense. Defensively, the Colts match up well against Eli Manning, who threw three picks against a decent, but not great, Carolina secondary.
Keys to The Rise: Dallas Clark. With the Giants linebackers unable to defend the pass, look for Manning to hit Clark early and often. Defensively, the Colts will miss Bob Sanders—who is out indefinitely with a torn biceps tendon—in trying to stop New York's ground game. If they can stop the run, the Colts win.