Obviously, different leagues keep different statistics.
Some penalize more for picks and fumbles, others don't penalize for them at all. Some award points for every 10 yards rushing, some bump it up to 25, and some only count touchdowns.
It's primarily a matter of the settings.
Still, there are some constants and factors to always pay attention to.
The 49ers team has grown a lot this offseason, and although the skill positions remain fairly untouched, the invisible contributers between the statistics are present: Two first round linemen, a new special teams coordinator, the same offensive coordinator (for once), and a defense insatiably hungry for wins.
This could, and should, be the best season for 49ers in fantasy football leagues in recent history.