Chile and Switzerland come into Monday's game tied atop the Group H standings following victories in their opening matches.
Chile defeated Honduras, while Switzerland pulled off a monumental upset over Spain.
Both teams will be looking to improve to six points with a win Monday, which would almost certainly guarantee them a spot in the knockout round.
Here are some of the top players to keep an eye on in today's match between Chile and Switzerland.
Fernandes scored the only goal in Switzerland's victory over Spain.
The 23 year-old midfielder scored just his second goal of international play against Spain, but he will look to increase that total against Chile.
Beausejour scored the only goal in Chile's 1-0 victory over Honduras.
Beausejour has been a leader on the Chilean team for a while now. He started 11 games for Chile in World Cup qualifying, and he was an integral figure in helping Chile get to the big stage.
The young Chilean forward turned in a great performance against Honduras. He had four shots and was a key part of Chile's dominance in controlling the action.
Sanchez became a regular in the starting lineup during World Cup qualifying for Chile, and he scored two goals in a victory over Bolivia.
Sanchez has been hyped up greatly throughout his young career. In 2008, he was a candidate for the Golden Boy award in Italy, which is given to the most promising players under 21. In 2007, Sanchez was named as one of the top 50 teenagers in world soccer according to World Soccer Magazine.
Suazo, the Chilean forward, has a great ability to put the ball in the back of the net.
Suazo holds the single season record for goals scored in the Chilean League at 51, a record set in 2006. He also scored 10 goals to lead all scorers in South American qualifying for the World Cup.
Suazo is questionable coming into Monday's game with Switzerland because of a thigh injury, but the Swiss will definitely have to keep a close eye on him if he plays.
The Swiss captain was announced as doubtful for Monday's game against Chile after missing the opener with a leg injury.
Despite this, he was on the starting lineup Monday morning prior to the beginning of Switzerland's match against Chile.
Frei is the all-time leading scorer for Switzerland. Despite being 30 years old, the Swiss forward still poured in five goals for his country during World Cup qualifying.