Who has the best shot?
Ohio State. The Buckeyes had a serious case for a No. 1 seed, so odds are this team isn't going out in second round.
Both teams the Buckeyes could face in the second round do pose serious matchup problems.
Oklahoma State might be slightly over-seeded as a seven seed, but two-guard James Anderson can go bucket-for-bucket with soon-to-be National Player of the Year Evan Turner.
If Georgia Tech beats Oklahoma State (which is likely with G-Tech's athleticism and length), then the Yellow Jackets will tower above the Buckeyes.
Who can knock off Ohio State?
Georgia Tech stands the best shot. The Yellow Jackets defend very well, making scoring in the paint a living hell for opponents.
Evan Turner does the majority of his scoring inside the arc which will be cause for concern for Ohio State.
When OSU isn't scoring behind Turner in the paint, it is dropping three-balls, but with Georgia Tech's length and athleticism, getting clean looks from deep may also be an issue.
Georgia Tech doesn't score well but crashes the glass very well (18th in the country in offensive rebounding). Ohio State is undersized and generally plays a four-guard set which is one reason why Turner's rebounding numbers are so impressive.
If G-Tech can impose its will on the glass and its size is a problem, the team that has the best shot of beating Kansas, could be out in the second round.
Sorry, you have no shot.
UC-Santa Barbara. Plain and simple, the Gauchos cannot score. If they were going to upset Ohio State, they'd need some size, but UCSB is lacking in the girth department, which means a loss by single-digits is a victory for the Big West.