The Rams had the luxury of the second overall pick last season, and OT stud Jason Smith fell into their lap, after Matthew Stafford was selected first.
Rams' management knew they needed offensive line help, and figured Smith would shore up their offensive line for a very long time. This resembles the Bills' current predicament, with no long term answer currently on the roster to protect that ever important blind side.
Their second round pick was inside linebacker James Laurinitis, a highly productive, instinctive backer, that had "can start immediately" written all over him. Buffalo must provide Paul Posluszny with help if they ever want to see his true potential, and nabbing an elite inside linebacker would do the trick (yes, I'm petitioning for Poz to move outside).
St. Louis picked running back-gobbler Dorrell Scott in the third round last year. Though not a huge name out of Clemson, Scott was a perfect fit for a big time Rams' need. Buffalo seems to be content with their interior defensive line of Kyle Williams, Marcus Stroud, and Spencer Johnson, but don't sleep on Bills brass eying a young and athletic big man with a high motor.
Stroud isn't getting any younger, and a possible switch to the 3-4 means the more tackles the better.
In rounds five and seven St. Louis took WR Brooks Foster out of North Carolina, and Chris Ogbonnaya from Texas. Both players were surely gliding under the radar and probably for good reasons. However, both were luxury additions that added strength and depth to their skill positions.
This is something I'm favoring the Bills to do. If a speedy scat-back is available in the later rounds, Buffalo could snatch him up, and with the departure of Terrell Owens looming, the Bills could use fresh legs at the wideout position.