The club put out the following message on their Twitter account on Thursday:
"Aubameyang has been removed from the squad for tomorrow's match for disciplinary reasons," read the post, per Stephan Uersfeld of ESPN FC.
No further explanation was provided by the Bundesliga side, who have recently relinquished top spot in the German top flight to rivals Bayern Munich after a difficult run of form.
Bundesliga writer Lars Pollmann speculated that the offence committed by Aubameyang is a severe one and noted the players haven't been at the training ground too much lately:
As we can see courtesy of Sport, the forward spent some time off during the international break visiting former team-mate Ousmane Dembele in Barcelona:
As noted above, this is not the first time BVB's star striker has been suspended by the football club.
In November last year, Aubameyang went to Milan and broke a curfew, meaning he sat out the side's clash with Sporting CP in the UEFA Champions League.
When he has been on the field, the 28-year-old has not been at his blistering best, with his own slump in form coinciding with that of the team's. He's gone five matches without a goal, with his previous strikes coming in October's 3-2 defeat to RB Leipzig.
However, as noted by WhoScored.com last month, Aubameyang has been among the most prolific players in European football for a long time:
So while he's not been at his most predatory as of late, there's no doubt Dortmund will be worse off without the searing pace and clinical finishing of their star striker.
Peter Bosz's team have been on a torrid run as of late, with the only win in their last seven matches coming against Magdeburg in the German Cup. It means they've slipped down the table and handed the title initiative back to rivals Bayern Munich.
Dortmund have some massive games coming up, too. After Friday's clash, they face Tottenham Hotspur in the Champions League before a showdown with their local rivals Schalke 04 in the Bundesliga.
When Aubameyang returned from suspension a year ago, he netted four times in the next game. BVB supporters will be hopeful he can make a similar recovery after this latest discretion.