As seen in the following video courtesy of MLB's official Twitter account, the injury occurred on a play at the plate when Royals teammate and Italy catcher Drew Butera fell into Perez's knee:
Jon Heyman of Today's Knuckleball reported the initial diagnosis appears to be inflammation, and he is expected to be OK. Venezuela's official team account announced an MRI revealed no structural damage, per Jeffrey Flanagan of MLB.com.
Venezuela manager Omar Vizquel said after the game that Perez was set to undergo testing, according to ESPN.com: "The update on Salvador Perez is he's got a loose knee, and he's got to go to the clinic and have some X-rays done to see if everything is going to be fine with him. So he's a question mark right now."
Per ESPN's Marly Rivera, Perez reportedly reached out to the Royals to tell them the injury isn't severe.
Perez was enjoying a strong game prior to being removed, as he was 2-for-4 with one home run, two runs and two RBI.
The 26-year-old is among the best catchers in baseball with four consecutive All-Star appearances and Gold Gloves to his credit, as well as a World Series MVP nod in 2015.
Last season, Perez hit a career-high 22 home runs to go with a .247 batting average and 64 RBI.
If Perez misses additional time in the WBC, Robinson Chirinos is in line to see the bulk of the innings for Venezuela behind the plate.
Should his ailment impact Perez's availability for the MLB regular season, Butera will be forced into service for the Royals.