Their season was given a huge boost on Thursday as they qualified for the UEFA Europa League quarter-finals with a 3-1 aggregate win over Manchester United.
However, Klopp was not getting carried away as to how the win could impact Liverpool's season ahead of a key clash with the Saints, per the club's Twitter feed:
JK: "The problem with confidence is that it's a little flower and if you step on it it's gone in a second." #LFC— Liverpool FC (@LFC) March 18, 2016
He also insisted that he was not setting targets for his side despite being only seven points back with a game in hand over fourth-placed Manchester City in the Premier League, per the Mirror's James Whaling:
I can’t set targets. It makes not too much sense. There is only Southampton then we have two weeks break where all the players are around the world. That’s pretty difficult. Hopefully we have a good lineup against Southampton because it was intense yesterday. We need to figure out who will be available.
Philippe Coutinho cancelled out Anthony Martial's penalty at Old Trafford, and Liverpool were comfortable on the night after claiming a 2-0 lead in the opening leg at Anfield.
Klopp's choice of attire prompted some comments, per Liverpool:
The boss shows his love for The Beatles... https://t.co/XjP2SCDmI2— Liverpool FC (@LFC) March 18, 2016
The German manager said it was "possible" for his side to go on and win the Europa League, but he was eager to point out there is still some way to go, per Whaling.
Liverpool's last meeting with Southampton in the league resulted in a 1-1 draw in October.
Klopp insisted his side will need to be "really good" if they are to prevail and said it was a relief his opposite number Ronald Koeman would not be playing, per the Liverpool Echo's James Pearce:
Klopp: "Ronald Koeman was a world class player as well so don't compare him to me! Thankfully, we don't have to play against Ronald Koeman,"— James Pearce (@JamesPearceEcho) March 18, 2016
He also gave an update on Alberto Moreno's injury, per ESPN FC's Ben Dinnery:
Alberto Moreno will have another scan on his hamstring today. But Klopp "is hopeful" he could be involved on Sunday. #LFC— Ben Dinnery (@BenDinnery) March 18, 2016
With United playing Manchester City on Sunday—both sides are above Liverpool in the table, as are Southampton—one or both are guaranteed to drop points.
Thus a victory over Koeman's men would see Liverpool make some gains on those above them and potentially set up a successful end to the season for the Anfield club.