After floundering in Chip Kelly's up-tempo scheme with the Philadelphia Eagles two years ago, the 29-year-old rediscovered the form he harnessed in 2014 en route to winning a rushing title throughout his first season with the Titans.
Appearing in all 16 games, Murray rushed 293 times for 1,287 yards and nine touchdowns. He also tallied 53 receptions for 377 yards and three scores.
Should Murray miss snaps, the Titans will deploy second-year back and former Heisman Trophy winner Derrick Henry as their primary rusher.
Henry showed promise last season in his backup role, rushing for 490 yards and five scores. He's a capable backup for Murray in Tennessee's ascendant offense that also includes quarterback Marcus Mariota and rookie wideout Corey Davis, who also suffered a hamstring injury and is undergoing an MRI, per Wyatt.