Tennessee @ Pittsburgh: This game will be very, very physical. Of course, the back story here is what happened after Tennessee beat the Steelers last season when LenDale White and some of his teammates stomped on the "Terrible Towel." I think that's something the fans care about more than the players, so it shouldn't really factor into the game. However, the fans at Heinz Field, along with Pittsburgh's defense, will make it tough for the Titans to pull out the victory. The Steelers have won six straight season openers and I don't see that ending here.
Pittsburgh wins, 28-10.
Miami @ Atlanta: Last year's two Cinderella teams face off in the opener. Fans are expecting big things from Atlanta's offense this year, and while the Dolphins will be able to slow the Falcons a bit, Atlanta still has too many weapons. Chad Pennington won't make any mistakes, but he also won't do enough for the win.
Atlanta wins, 26-14.
Cincinnati wins, 34-13.
Minnesota @ Cleveland: This one should be interesting. For some reason, Eric Mangini thought that not naming his starting quarterback until a few days before the season opens would give his team some kind of competitive advantage. On the other hand, Brad Childress' team begins what will probably be a make or break season for him. His team has the talent. He's bet the house on Brett Favre. Look for the Vikings to get off to a good start because the Browns are a mess.
Minnesota wins, 20-7.
Jacksonville @ Indianapolis: I'm not very high on either of these teams, but they always seem to play each other very close. This will be no different. Maurice Jones-Drew will have a very good game, but the Jags will come up just short.
Indy wins, 19-17.
Detroit @ New Orleans: The Lions will have to wait a little bit longer for their first victory (that mattered) since 2007. The Saints' offense will be just as potent as it was last year and their defense will surprise people this year. New Orleans takes this easily.
New Orleans wins, 37-17.
Dallas @ Tampa Bay: Another interesting game. For the first time in a while, things in Dallas have been pretty quiet. That is a good thing for the Cowboys and probably a bad thing for the Bucs. Tampa is definitely in rebuilding mode, while the Cowboys are looking to prove people wrong. Tony Romo should have a good day.
Dallas wins, 28-14.
Philadelphia @ Carolina: Carolina has to get off to a fast start if they are going to win this game. They have to make Philly one-dimensional if they are going to win. Jake Delhomme has to play mistake-free ball for them to win. Carolina has a great backfield but if Philly can stack the box and at least contain Steve Smith, they will win.
Philly wins, 24-21.
Baltimore wins, 31-9 (Lock of the Week).
New York Jets @ Houston: Mark Sanchez will really struggle here. Between Mario Williams and DeMeco Ryans constantly being in his face and Houston's offense putting up big numbers, the Texans should be able to get the season off on a great start.
Houston wins, 27-13.
New York Giants win, 13-10.
Arizona wins, 28-14.
St. Louis @ Seattle: Seattle feels like they can get back to where they were before last year. Stephen Jackson will give them a good amount of trouble, but the Rams just don't have the weapons to win this one. Seattle is also one of the toughest places in the league to play.
Seattle wins, 21-6.
Chicago @ Green Bay: This will be one of the best games of the opening weekend. Both teams have pretty high expectations coming into the season, and neither team wants to start off with a loss. Green Bay has looked fantastic while their starters were playing this preseason. Their offense will play great here and just edge out Chicago.
Green Bay wins, 24-20.
Buffalo @ New England: The Golden Boy's return comes on Monday night as the Pats begin their quest towards a fourth Super Bowl victory in the decade. Buffalo's offense has looked pretty horrible this preseason (although T.O. didn't play much), so New England's new-look defense won't be tested too much.
New England wins, 26-7.
San Diego @ Oakland: This one will also be a little closer than most think, although I don't have too much confidence saying that the Raiders will make this close because it's the Raiders. San Diego will win regardless.
San Diego wins 30-21.