The Red Sox beat the Kansas City Royals 7-0 Monday night as 24-year-old left hander Jon Lester threw his first no-hitter.
Lester walked two and struck out nine.
Lester was backed by great defensive plays from center fielder Jacoby Ellsbury, first baseman Kevin Youkilis, and shortstop Julio Lugo.
The final out came when Lester struck out Alberto Callaspo on a 1-2 count.
The game was played at Fenway Park in Boston to an enthusiastic crowd, who stood through the entire ninth inning in support of their pitcher.
Lester became only the second pitcher in history to pitch a no-hitter against the Royals.
Lester was diagnosed in 2006 with blood cancer and has now crowned his triumphant return to major league baseball.