After two 8-8 seasons in a row are head coach Gary Kubiak and GM Rick Smith a losing season away from new jobs?
How is the health of quarterback Matt Schaub and will he be able to play more than 12 games for the first time in his career?
How will the contract situations of LB DeMeco Ryans, TE Owen Daniels, and CB Dunta Robinson (holdout) affect the Texans team?
Will the other first round draft picks on the Texans defensive line start playing to the Pro Bowl level of DE Mario Williams?
Will the additions of LB Brian Cushing and DE Connor Barwin in the 2009 NFL Draft help a defense that allowed a whopping 394 points in 2008?
How will the Colts handle the departure of Super Bowl winning head coach Tony Dungy?
Is quarterback Peyton Manning healthy (knee) and will the offensive line with return of OT Tony Ugoh (knee) be ready to protect him?
What will the role of former “retired” assistant coaches Tom Moore and Howard Mudd be with the Colts on a daily basis and how will their units react?
Is new head coach Jim Caldwell ready to step out of the shadow of Tony Dungy and will he be able to continue the Colts record six straight 12-win seasons?
How healthy are the Colts defensively SS Bob Sanders (knee) and CB Marlin Jackson (knee)and will their defensive unit be able to continue to perform at a high level (298 points allowed in ’08)?
Despite having only two losing seasons over six years, if the Jaguars have another losing season will on the hot seat head coach Jack Del Rio be looking for another job next season?
Is quarterback David Garrard ready to live up to his huge contract or was 2007 his high-water mark that may never be seen again?
Is getting rid of Reggie Williams, Matt Jones, and Jerry Porter while adding free agent pickup Torry Holt the answer to the Jaguars receiving woes or is more needed?
Is RB Maurice Jones-Drew ready to live-up to his new contract (four-year, $31 Million contract includes $17.5 million guaranteed) and can he replace the production of departed veteran Fred Taylor?
How is the health of the Jaguars O-line (6 offensive lineman on I\R in ‘08) and will the additions of OT Tra Thomas and 2009 draft picks Eugene Monroe and Eben Britton help solidify this group?
Will the Titans and head coach Jeff Fisher be able to rebound after going 10-0 to start the 2008 season then fizzling out with a home loss to the Ravens in the playoffs?
Is quarterback Kerry Collins still the answer at the quarterback position or is former 2006 NFL Rookie of the Year Vince Young ready for a comeback season?
What will the Titans’ backfield look like now that Chris Johnson says he no longer wants to be part of the “Smash and Dash” nickname along fellow back LenDale White and are there enough carries for the two backs?
Will the Titans’ defense be the same (allowed only 234 points in 2008) now that free agent DT Albert Haynesworth has moved on to the Redskins and who will replace the Pro Bowl player?
Who is going to be the Titans feature receiver (Justin Gage or others) and will the addition of rookie Kenny Britt in the NFL Draft help their receivers unit?
Lloyd Vance is a Sr. NFL Writer for Taking It to the House and an award winning member of the Pro Football Writers of America (PFWA)