College Football Week 2 Predictions: Picking Top 25 Games Against the Spread

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College Football Week 2 Predictions: Picking Top 25 Games Against the Spread
Ryan Kang/Associated Press

Week 1 of the college football season reminded us that handicapping games with point spreads is a difficult proposition. Oklahoma dominated Louisiana Tech as a 33.5-point favorite, looking the part of a hefty chalk in all four quarters. Then, with the starters long departed, the Bulldogs scored a meaningless touchdown with roughly a half-minute remaining.

This end-zone trip pushed the final score to 48-16, and like that, Louisiana Tech secured a cover against the Sooners’ backups’ backups’ backups. The tickets that looked so promising for so long were sent to the wastebaskets.

The season had returned.

After a .500-ish debut our picks against the spread in Week 1, we’re turning our focus to Week 2. We have a new AP poll, which will be used to outline the teams being targeted, along with a few fabulous matchups. 

Oregon and Michigan State, we welcome you with open arms and full koozies.

The only difference this week, however, is games featuring Top 25 teams taking on FCS opponents—which includes Florida State, Texas A&M, Baylor, LSU and others—will not be picked. At the time this post was being crafted, there were no point spreads available for these matchups. (Don’t blame the sportsbooks; blame these dreadful early schedules.)

As for those that are being handicapped, here are the Week 2 picks.


All spreads are courtesy of unless noted otherwise.

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