Chapman needed 16 pitches to lock down the 3-0 victory, earning his 23rd save of the season in rather easy fashion.
All but two of his pitches were fastballs, with the slowest registering at 98 miles per hour and the fastest at 103 mph. That 103-mph heater came on the final pitch of the game, when Chapman struck out Diamondbacks shortstop Didi Gregorius to preserve the win for starter Mike Leake.
The 26 year-old Cuban flamethrower is in his fifth MLB season but only his third as the Reds closer. Chapman, who debuted in 2010, had only one save through his first two seasons. As the team's designated closer, he turned in stellar performances the past two seasons with 38 saves in both 2012 and 2013.
Chapman is the fifth pitcher to earn 100 saves in a Reds uniform, joining Clay Carroll (119), John Franco (148), Francisco Cordero (150) and franchise saves leader Danny Graves (182).
The Cuban's career ERA of 2.37 is second in franchise history for a closer, trailing only Jeff Shaw's 2.31 (minimum 50 saves), per MLB.com.
Cincinnati's single-season saves record belongs to Jeff Brantley, who recorded 44 in 1996.
Chapman owns the MLB record for consecutive appearances with a strikeout, as Tuesday's punchout of Gregorius extended the lefty's own record to 45 games, per MLB.com's Steve Gilbert.